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A higher grade indicates a more aggressive cancer that is more likely to spread quickly.
The most common scale used to evaluate the grade of prostate cancer cells is called a Gleason score.
Gleason scoring combines two numbers and can range from 2 (nonaggressive cancer) to 10 (very aggressive cancer).
In addition, genomic testing in increasingly being used to more accurately assess risk and detect aggressive prostate cancer.
Hence, debate continues surrounding prostate cancer screening.
Radical prostatectomy carries a risk of urinary incontinence and erectile dysfunction.Mayo Clinic also leverages MRI-TRUS fusion technology, which blends (fuses) images from an MRI scan and transrectal ultrasound (TRUS) to create a more-precise 360-degree prostate map, which in turn can improve prostate biopsy accuracy.Mayo Clinic is also the first medical center in the United States approved by the Food and Drug Administration to prepare and administer C-11 choline PET scanning to help detect recurrent prostate cancer at its earliest stages — before it can be detected by other imaging tests — and enable more-precise targeting for follow-up treatment.When a biopsy confirms the presence of cancer, the next step is to determine the level of aggressiveness (grade) of the cancer cells.
A laboratory pathologist examines a sample of your cancer to determine how much cancer cells differ from the healthy cells.
Whether to test healthy men with no symptoms for prostate cancer is controversial.